STATISTICAL GENETICS Gene Mapping Through Linkage and Association

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References from Statistical Genetics: Gene Mapping Through Linkage and Association

A-C D-F G-K L-N O-R S-T U-Z Online Material

S.A.G.E. (2006). v5.2 Statistical Analysis for Genetic Epidemiology. http://darwin.cwru.edu/sage/.

Saccone, S. F., Rice, J. P., & Saccone, N. L. (2006). Power-based, phase-informed selection of single nucleotide polymorphisms for disease association screens. Genet Epidemiol, 30(6), 459-470 Abstract

Sachidanandam, R., Weissman, D., Schmidt, S. C., Kakol, J. M., Stein, L. D., Marth, G., Sherry, S., Mullikin, J. C., Mortimore, B. J., Willey, D. L., Hunt, S. E., Cole, C. G., Coggill, C., Rice, C. M., Ning, Z., Rogers, J., Bentley, D. R., Kwok, Y., Mardis, E. R., Yeh, R. T., Schultz, B., Cook, L., Davenport, R., Dante, M., Fulton, L., Hillier, L., Waterston, R. H., McPherson, J. D., Gilman, B., Schaffner, S., Van Etten, W. J., Reich, D., Higgins, J., Daly, M. J., Blumenstiel, B., Baldwin, J., Stange-Thomann, N., Zody, M. C., Linton, L., Lander, E. S., & Altshuler, D. (2001). A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms. Nature, 409(6822), 928-933 Abstract

Saiki, R. K., Gelfand, D. H., Stoffel, S., Scharf, S. J., Higuchi, R., Horn, G. T., Mullis, K. B., & Erlich, H. A. (1988). Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase. Science, 239(4839), 487-491 Abstract

Saris, W. E., & Satorra, A. (1993). Power evaluations in structural equation models. In Bollen, K. A. & Long, J. S. (Eds.), Testing Structural Equation Models (p181-204). Newbury Park, CA: Sage.

Sasieni, D. (1997). From genotypes to genes: doubling the sample size. Biometrics, 53(4), 1253-1261 Abstract

Satagopan, J. M., Verbel, D. A., Venkatraman, E. S., Offit, K. E., & Begg, C. B. (2002). Two-stage designs for gene-disease association studies. Biometrics, 58(1), 163-170 Abstract

Satagopan, J. M., & Elston, R. C. (2003). Optimal two-stage genotyping in population-based association studies. Genet Epidemiol, 25(2), 149-157 Abstract

Satagopan, J. M., Venkatraman, E. S., & Begg, C. B. (2004). Two-stage designs for gene-disease association studies with sample size constraints. Biometrics, 60(3), 589-597 Abstract

Satorra, A., & Saris, W. E. (1985). The power of the likelihood ratio test in covariance structure analysis. _Psychometrika _, 50, 83-90

Satten, G. A., Flanders, W. D., & Yang, Q. (2001). Accounting for unmeasured population substructure in case-control studies of genetic association using a novel latent-class model. Am J Hum Genet, 68(2), 466-477 Abstract

Sawcer, S., Jones, H. B., Judge, D., Visser, F., Compston, A., Goodfellow, N., & Clayton, D. (1997). Empirical genomewide significance levels established by whole genome simulations. Genet Epidemiol, 14(3), 223-229 Abstract

Saxena, R., de Bakker, I., Singer, K., Mootha, V., Burtt, N., Hirschhorn, J. N., Gaudet, D., Isomaa, B., Daly, M. J., Groop, L., Ardlie, K. G., & Altshuler, D. (2006). Comprehensive association testing of common mitochondrial DNA variation in metabolic disease. Am J Hum Genet, 79(1), 54-61 Abstract

Schafer, J. L. (1997). Analysis of Incomplete Multivariate Data. London: Chapman and Hall.

Schafer, J. L. (1999). Multiple imputation: a primer. Stat. Methods Med. Res, 8, 3-15

Schafer, J. L., & Graham, J. W. (2002). Missing data: our view of the state of the art. Psychol Methods, 7(2), 147-177 Abstract

Schaffner, S. F., Foo, C., Gabriel, S., Reich, D., Daly, M. J., & Altshuler, D. (2005). Calibrating a coalescent simulation of human genome sequence variation. Genome Res, 15(11), 1576-1583 Abstract

Schaid, D. J., & Sommer, S. S. (1994). Comparison of statistics for candidate-gene association studies using cases and parents. Am J Hum Genet, 55(2), 402-409 Abstract

Schaid, D. J., Rowland, C. M., Tines, D. E., Jacobson, R. M., & Poland, G. A. (2002). Score tests for association between traits and haplotypes when linkage phase is ambiguous. Am J Hum Genet, 70(2), 425-434

Schlesselman, J. J. (1982). Case-Control Studies: Design, Conduct, Analysis.. New York, NY.: Oxford University Press.

Schmitz, S., Cherny, S. S., & Fulker, D. W. (1998). Increase in power through multivariate analyses. Behav Genet, 28(5), 357-363 Abstract

Schork, N. J. (1993). Extended multipoint identity-by-descent analysis of human quantitative traits: efficiency, power, and modeling considerations. Am J Hum Genet, 53(6), 1306-1319 Abstract

Schork, N. J., Allison, D. B., & Thiel, B. (1996). Mixture distributions in human genetics research. Stat Methods Med Res, 5(2), 155-178 Abstract

Schuit, S. C., van Meurs, J. B., Bergink, A. P., van der Klift, M., Fang, Y., Leusink, G., Hofman, A., van Leeuwen, J. P., Uitterlinden, A. G., & Pols, H. A. (2004). Height in pre- and postmenopausal women is influenced by estrogen receptor alpha gene polymorphisms. J Clin Endocrinol Metab, 89(1), 303-309 Abstract

Schulze, T. G., Buervenich, S., Badner, J. A., Steele, C. J., Detera-Wadleigh, S. D., Dick, D., Foroud, T., Cox, N. J., MacKinnon, D. F., Potash, J. B., Berrettini, W. H., Byerley, W., Coryell, W., DePaulo, J. R., Jr., Gershon, E. S., Kelsoe, J. R., McInnis, M. G., Murphy, D. L., Reich, T., Scheftner, W., Nurnberger, J. I., Jr., & McMahon, F. J. (2004). Loci on chromosomes 6q and 6p interact to increase susceptibility to bipolar affective disorder in the national institute of mental health genetics initiative pedigrees. Biol Psychiatry, 56(1), 18-23 Abstract

Schymick, J. C., Scholz, S. W., Fung, H. C., Britton, A., Arepalli, S., Gibbs, J. R., Lombardo, F., Matarin, M., Kasperaviciute, D., Hernandez, D. G., Crews, C., Bruijn, L., Rothstein, J., Mora, G., Restagno, G., Chio, A., Singleton, A., Hardy, J., & Traynor, B. J. (2007). Genome-wide genotyping in amyotrophic lateral sclerosis and neurologically normal controls: first stage analysis and public release of data. Lancet Neurol, 6(4), 322-328 Abstract

Searle, S. R. (1982). Matrix Algebra Useful for Statistics. New York, NY.: Wiley-Interscience.

Sebastiani, P., Lazarus, R., Weiss, S. T., Kunkel, L. M., Kohane, I. S., & Ramoni, M. F. (2003). Minimal haplotype tagging. Proc Natl Acad Sci U S A, 100(17), 9900-9905 Abstract

Sebat, J., Lakshmi, B., Troge, J., Alexander, J., Young, J., Lundin, P., Maner, S., Massa, H., Walker, M., Chi, M., Navin, N., Lucito, R., Healy, J., Hicks, J., Ye, K., Reiner, A., Gilliam, T. C., Trask, B., Patterson, N., Zetterberg, A., & Wigler, M. (2004). Large-scale copy number polymorphism in the human genome. Science, 305(5683), 525-528 Abstract

Sebat, J., Lakshmi, B., Malhotra, D., Troge, J., Lese-Martin, C., Walsh, T., Yamrom, B., Yoon, S., Krasnitz, A., Kendall, J., Leotta, A., Pai, D., Zhang, R., Lee, Y. H., Hicks, J., Spence, S. J., Lee, A. T., Puura, K., Lehtimaki, T., Ledbetter, D., Gregersen, K., Bregman, J., Sutcliffe, J. S., Jobanputra, V., Chung, W., Warburton, D., King, M. C., Skuse, D., Geschwind, D. H., Gilliam, T. C., Ye, K., & Wigler, M. (2007). Strong association of de novo copy number mutations with autism. Science, 316(5823), 445-449 Abstract

Seldin, M. F., Shigeta, R., Villoslada, P., Selmi, C., Tuomilehto, J., Silva, G., Belmont, J. W., Klareskog, L., & Gregersen, K. (2006). European population substructure: clustering of northern and southern populations. PLoS Genet, 2(9), e143 Abstract

Self, S. G., & Liang, K. Y. (1987). Asymptotic properties of maximum

likelihood estimators and likelihood ratio tests under nonstandard conditions. J. Am. Stat. Assoc, 82, 605-610

Sham, C. (1998). Statistics in Human Genetics. London: Arnold.

Sham, C., Cherny, S. S., Purcell, S., & Hewitt, J. K. (2000). Power of linkage versus association analysis of quantitative traits, by use of variance-components models, for sibship data. Am J Hum Genet, 66(5), 1616-1630 Abstract

Sham, C., Zhao, J. H., Cherny, S. S., & Hewitt, J. K. (2000). Variance-Components QTL linkage analysis of selected and non-normal samples: conditioning on trait values. Genet Epidemiol, 19 Suppl 1, S22-28 Abstract

Sham, C., & Purcell, S. (2001). Equivalence between Haseman-Elston and variance-components linkage analyses for sib pairs. Am J Hum Genet, 68(6), 1527-1532 Abstract

Sham, C., Purcell, S., Cherny, S. S., & Abecasis, G. R. (2002). Powerful regression-based quantitative-trait linkage analysis of general pedigrees. Am J Hum Genet, 71(2), 238-253 Abstract

Sham, C., Rijsdijk, F. V., Knight, J., Makoff, A., North, B., & Curtis, D. (2004). Haplotype association analysis of discrete and continuous traits using mixture of regression models. Behav Genet, 34(2), 207-214

Shaw, F. H., & Geyer, C. J. (1997). Estimation and testing in constrained covariance component models. Biometrika, 84, 95-102

Shete, S., & Amos, C. I. (2002). Testing for genetic linkage in families by a variance-components approach in the presence of genomic imprinting. Am J Hum Genet, 70(3), 751-757 Abstract

Shete, S., & Zhou, X. (2005). Parametric approach to genomic imprinting analysis with applications to Angelman’s syndrome. Hum Hered, 59(1), 26-33 Abstract

Skol, A. D., Scott, L. J., Abecasis, G. R., & Boehnke, M. (2006a). Joint analysis is more efficient than replication-based analysis for two-stage genome-wide association studies. Nat Genet, 38(2), 209-213 Abstract

Skol, A. D., Scott, L. J., Abecasis, G. R., & Boehnke, M. (2006b). Corrigendum: Joint analysis is more efficient than replication-based analysis for two-stage genome-wide association studies. Nat Genet, 38, 390 Abstract

Sladek, R., Rocheleau, G., Rung, J., Dina, C., Shen, L., Serre, D., Boutin, P., Vincent, D., Belisle, A., Hadjadj, S., Balkau, B., Heude, B., Charpentier, G., Hudson, T. J., Montpetit, A., Pshezhetsky, A. V., Prentki, M., Posner, B. I., Balding, D. J., Meyre, D., Polychronakos, C., & Froguel, (2007). A genome-wide association study identifies novel risk loci for type 2 diabetes. Nature, 445(7130), 881-885 Abstract

Smith, C. A. (1963). Testing for Heterogeneity of Recombination Fraction Values in Human Genetics. Ann Hum Genet, 27, 175-182 Abstract

Smith, F. M., Garfield, A. S., & Ward, A. (2006). Regulation of growth and metabolism by imprinted genes. Cytogenet Genome Res, 113(1-4), 279-291 Abstract

Snieder, H., van Doornen, L. J. P., & Boomsma, D. I. (1995). Developmental genetic trends in blood pressure levels and blood pressure reactivity to stress. In Turner, J. R., Cardon, L. R. & Hewitt, J. K. (Eds.), Behavior Genetic Approaches in Behavioral Medicine (p105-130). New York, NY: Plenum Press.

Snieder, H., van Doornen, L. J., & Boomsma, D. I. (1997). The age dependency of gene expression for plasma lipids, lipoproteins, and apolipoproteins. Am J Hum Genet, 60(3), 638-650 Abstract

Sobel, E., & Lange, K. (1996). Descent graphs in pedigree analysis: applications to haplotyping, location scores, and marker-sharing statistics. Am J Hum Genet, 58(6), 1323-1337 Abstract

Sobel, E., Sengul, H., & Weeks, D. E. (2001). Multipoint estimation of identity-by-descent probabilities at arbitrary positions among marker loci on general pedigrees. Hum Hered, 52(3), 121-131 Abstract

Sobel, E., Papp, J. C., & Lange, K. (2002). Detection and integration of genotyping errors in statistical genetics. Am J Hum Genet, 70(2), 496-508 Abstract

Sobell, J. L., Heston, L. L., & Sommer, S. S. (1993). Novel association approach for determining the genetic predisposition to schizophrenia: case-control resource and testing of a candidate gene. Am J Med Genet, 48(1), 28-35 Abstract

Sorensen, D., & Gianola, D. (2002). Likelihood, Bayesian, and MCMC Methods in Quantitative Genetics.. New York, NY: Springer.

Spielman, R. S., McGinnis, R. E., & Ewens, W. J. (1993). Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM). Am J Hum Genet, 52(3), 506-516 Abstract

Spielman, R. S., & Ewens, W. J. (1998). A sibship test for linkage in the presence of association: the sib transmission/disequilibrium test. Am J Hum Genet, 62(2), 450-458 Abstract

Stefansson, H., Helgason, A., Thorleifsson, G., Steinthorsdottir, V., Masson, G., Barnard, J., Baker, A., Jonasdottir, A., Ingason, A., Gudnadottir, V. G., Desnica, N., Hicks, A., Gylfason, A., Gudbjartsson, D. F., Jonsdottir, G. M., Sainz, J., Agnarsson, K., Birgisdottir, B., Ghosh, S., Olafsdottir, A., Cazier, J. B., Kristjansson, K., Frigge, M. L., Thorgeirsson, T. E., Gulcher, J. R., Kong, A., & Stefansson, K. (2005). A common inversion under selection in Europeans. Nat Genet, 37(2), 129-137 Abstract

Stephens, M., & Donnelly, (2000). Inference in molecular population genetics. J. R. Stat. Soc. Ser. B, 62, 605-655

Stephens, M., Smith, N. J., & Donnelly, (2001). A new statistical method for haplotype reconstruction from population data. Am J Hum Genet, 68(4), 978-989 Abstract

Stephens, M., & Donnelly, (2003). A comparison of bayesian methods for haplotype reconstruction from population genotype data. Am J Hum Genet, 73(5), 1162-1169 Abstract

Stephens, M., & Scheet, (2005). Accounting for decay of linkage disequilibrium in haplotype inference and missing-data imputation. Am J Hum Genet, 76(3), 449-462 Abstract

Stine, O. C., Xu, J., Koskela, R., McMahon, F. J., Gschwend, M., Friddle, C., Clark, C. D., McInnis, M. G., Simpson, S. G., Breschel, T. S., Vishio, E., Riskin, K., Feilotter, H., Chen, E., Shen, S., Folstein, S., Meyers, D. A., Botstein, D., Marr, T. G., & DePaulo, J. R. (1995). Evidence for linkage of bipolar disorder to chromosome 18 with a parent-of-origin effect. Am J Hum Genet, 57(6), 1384-1394 Abstract

Storey, J. D., & Tibshirani, R. (2003). Statistical significance for genomewide studies. Proc Natl Acad Sci U S A, 100(16), 9440-9445 Abstract

Strachan, T., & Read, A. (1999). Human Molecular Genetics 2 (2nd ed.). Oxford: BIOS Scientific Publishers Ltd.

Stram, D. O., & Lee, J. W. (1994). Variance components testing in the longitudinal mixed effects model. Biometrics, 50(4), 1171-1177 Abstract

Stram, D. O., Haiman, C. A., Hirschhorn, J. N., Altshuler, D., Kolonel, L. N., Henderson, B. E., & Pike, M. C. (2003). Choosing haplotype-tagging SNPS based on unphased genotype data using a preliminary sample of unrelated subjects with an example from the Multiethnic Cohort Study. Hum Hered, 55(1), 27-36 Abstract

Stram, D. O., Leigh Pearce, C., Bretsky, P., Freedman, M., Hirschhorn, J. N., Altshuler, D., Kolonel, L. N., Henderson, B. E., & Thomas, D. C. (2003). Modeling and E-M estimation of haplotype-specific relative risks from genotype data for a case-control study of unrelated individuals. Hum Hered, 55(4), 179-190

Stram, D. O. (2004). Tag SNP selection for association studies. Genet Epidemiol, 27(4), 365-374

Stranger, B. E., Forrest, M. S., Clark, A. G., Minichiello, M. J., Deutsch, S., Lyle, R., Hunt, S., Kahl, B., Antonarakis, S. E., Tavare, S., Deloukas, P., & Dermitzakis, E. T. (2005). Genome-wide associations of gene expression variation in humans. PLoS Genet, 1(6), e78 Abstract

Strauch, K., Fimmers, R., Windemuth, C., Hahn, A., Wienker, T. F., & Baur, M. (1999). Linkage analysis with adequate modeling of a parent-of-origin effect. Genet Epidemiol, 17 Suppl 1, S331-336 Abstract

Strauch, K., Fimmers, R., Kurz, T., Deichmann, K. A., Wienker, T. F., & Baur, M. (2000). Parametric and nonparametric multipoint linkage analysis with imprinting and two-locus-trait models: application to mite sensitization. Am J Hum Genet, 66(6), 1945-1957 Abstract

Strauch, K., & Baur, M. (2005). Parent-of-origin, imprinting, mitochondrial, and X-linked effects in traits related to alcohol dependence: presentation Group 18 of Genetic Analysis Workshop 14. Genet Epidemiol, 29 Suppl 1, S125-132 Abstract

Stringham, H. M., & Boehnke, M. (1996). Identifying marker typing incompatibilities in linkage analysis. Am J Hum Genet, 59(4), 946-950 Abstract

Stringham, H. M., & Boehnke, M. (2001). Lod scores for gene mapping in the presence of marker map uncertainty. Genet Epidemiol, 21(1), 31-39 Abstract

Stumpf, M. P., & McVean, G. A. (2003). Estimating recombination rates from population-genetic data. Nat Rev Genet, 4(12), 959-968 Abstract

Suarez, B. K., Rice, J., & Reich, T. (1978). The generalized sib pair IBD distribution: its use in the detection of linkage. Ann Hum Genet, 42(1), 87-94 Abstract

Suarez, B. K., & Hodge, S. E. (1979). A simple method to detect linkage for rare recessive diseases: an application to juvenile diabetes. Clin Genet, 15(2), 126-136 Abstract

Sullivan, F., Eaves, L. J., Kendler, K. S., & Neale, M. C. (2001). Genetic case-control association studies in neuropsychiatry. Arch Gen Psychiatry, 58(11), 1015-1024 Abstract

Sullivan, F., Neale, B. M., Neale, M. C., van den Oord, E., & Kendler, K. S. (2003). Multipoint and single point non-parametric linkage analysis with imperfect data. Am J Med Genet B Neuropsychiatr Genet, 121(1), 89-94 Abstract

Surani, M. A., Barton, S. C., & Norris, M. L. (1984). Development of reconstituted mouse eggs suggests imprinting of the genome during gametogenesis. Nature, 308(5959), 548-550 Abstract

Sved, J. A. (1971). Linkage disequilibrium and homozygosity of chromosome segments in finite populations. Theor Popul Biol, 2(2), 125-141 Abstract

Szatmari, P., Paterson, A. D., Zwaigenbaum, L., Roberts, W., Brian, J., Liu, X. Q., Vincent, J. B., Skaug, J. L., Thompson, A. P., Senman, L., Feuk, L., Qian, C., Bryson, S. E., Jones, M. B., Marshall, C. R., Scherer, S. W., Vieland, V. J., Bartlett, C., Mangin, L. V., Goedken, R., Segre, A., Pericak-Vance, M. A., Cuccaro, M. L., Gilbert, J. R., Wright, H. H., Abramson, R. K., Betancur, C., Bourgeron, T., Gillberg, C., Leboyer, M., Buxbaum, J. D., Davis, K. L., Hollander, E., Silverman, J. M., Hallmayer, J., Lotspeich, L., Sutcliffe, J. S., Haines, J. L., Folstein, S. E., Piven, J., Wassink, T. H., Sheffield, V., Geschwind, D. H., Bucan, M., Brown, W. T., Cantor, R. M., Constantino, J. N., Gilliam, T. C., Herbert, M., Lajonchere, C., Ledbetter, D. H., Lese-Martin, C., Miller, J., Nelson, S., Samango-Sprouse, C. A., Spence, S., State, M., Tanzi, R. E., Coon, H., Dawson, G., Devlin, B., Estes, A., Flodman, P., Klei, L., McMahon, W. M., Minshew, N., Munson, J., Korvatska, E., Rodier, M., Schellenberg, G. D., Smith, M., Spence, M. A., Stodgell, C., Tepper, G., Wijsman, E. M., Yu, C. E., Roge, B., Mantoulan, C., Wittemeyer, K., Poustka, A., Felder, B., Klauck, S. M., Schuster, C., Poustka, F., Bolte, S., Feineis-Matthews, S., Herbrecht, E., Schmotzer, G., Tsiantis, J., Papanikolaou, K., Maestrini, E., Bacchelli, E., Blasi, F., Carone, S., Toma, C., Van Engeland, H., de Jonge, M., Kemner, C., Koop, F., Langemeijer, M., Hijimans, C., Staal, W. G., Baird, G., Bolton, F., Rutter, M. L., Weisblatt, E., Green, J., Aldred, C., Wilkinson, J. A., Pickles, A., Le Couteur, A., Berney, T., McConachie, H., Bailey, A. J., Francis, K., Honeyman, G., Hutchinson, A., Parr, J. R., Wallace, S., Monaco, A. P., Barnby, G., Kobayashi, K., Lamb, J. A., Sousa, I., Sykes, N., Cook, E. H., Guter, S. J., Leventhal, B. L., Salt, J., Lord, C., Corsello, C., Hus, V., Weeks, D. E., Volkmar, F., Tauber, M., Fombonne, E., & Shih, A. (2007). Mapping autism risk loci using genetic linkage and chromosomal rearrangements. Nat Genet, 39(3), 319-328 Abstract

Tabachnik, B. G., & Fidell, L. S. (2001). Using Multivariate Statistics. Boston, MA.: Allyn and Bacon.

Tanck, M. W., Klerkx, A. H., Jukema, J. W., De Knijff, P., Kastelein, J. J., & Zwinderman, A. H. (2003). Estimation of multilocus haplotype effects using weighted penalised log-likelihood: analysis of five sequence variations at the cholesteryl ester transfer protein gene locus. Ann Hum Genet, 67(Pt 2), 175-184 Abstract

Tapper, W., Collins, A., Gibson, J., Maniatis, N., Ennis, S., & Morton, N. E. (2005). A map of the human genome in linkage disequilibrium units. Proc Natl Acad Sci U S A, 102(33), 11835-11839 Abstract

Tavtigian, S. V., Simard, J., Teng, D. H., Abtin, V., Baumgard, M., Beck, A., Camp, N. J., Carillo, A. R., Chen, Y., Dayananth, P., Desrochers, M., Dumont, M., Farnham, J. M., Frank, D., Frye, C., Ghaffari, S., Gupte, J. S., Hu, R., Iliev, D., Janecki, T., Kort, E. N., Laity, K. E., Leavitt, A., Leblanc, G., McArthur-Morrison, J., Pederson, A., Penn, B., Peterson, K. T., Reid, J. E., Richards, S., Schroeder, M., Smith, R., Snyder, S. C., Swedlund, B., Swensen, J., Thomas, A., Tranchant, M., Woodland, A. M., Labrie, F., Skolnick, M. H., Neuhausen, S., Rommens, J., & Cannon-Albright, L. A. (2001). A candidate prostate cancer susceptibility gene at chromosome 17 Nat Genet, 27(2), 172-180 Abstract

Templeton, A. (2002). Out of Africa again and again. Nature, 416(6876), 45-51 Abstract

Templeton, A. R., Boerwinkle, E., & Sing, C. F. (1987). A cladistic analysis of phenotypic associations with haplotypes inferred from restriction endonuclease mapping. I. Basic theory and an analysis of alcohol dehydrogenase activity in Drosophila. Genetics, 117(2), 343-351

Templeton, A. R., Sing, C. F., Kessling, A., & Humphries, S. (1988). A cladistic analysis of phenotype associations with haplotypes inferred from restriction endonuclease mapping. II. The analysis of natural populations. Genetics, 120(4), 1145-1154 Abstract

Templeton, A. R., Crandall, K. A., & Sing, C. F. (1992). A cladistic analysis of phenotypic associations with haplotypes inferred from restriction endonuclease mapping and DNA sequence data. III. Cladogram estimation. Genetics, 132(2), 619-633 Abstract

Templeton, A. R., & Sing, C. F. (1993). A cladistic analysis of phenotypic associations with haplotypes inferred from restriction endonuclease mapping. IV. Nested analyses with cladogram uncertainty and recombination. Genetics, 134(2), 659-669 Abstract

Templeton, A. R., Weiss, K. M., Nickerson, D. A., Boerwinkle, E., & Sing, C. F. (2000). Cladistic structure within the human Lipoprotein lipase gene and its implications for phenotypic association studies. Genetics, 156(3), 1259-1275 Abstract

Terwilliger, J. D., Ding, Y., & Ott, J. (1992). On the relative importance of marker heterozygosity and intermarker distance in gene mapping. Genomics, 13(4), 951-956 Abstract

Terwilliger, J. D., & Ott, J. (1994). Handbook of Human Genetic Linkage. In (p237-238). Baltimore, MD: Johns Hopkins University Press.

Terwilliger, J. D. (1996). SIBPAIR: sibpair analysis on nuclear families. http://www.helsinki.fi/~tsjuntun/linkage/analyze/..

Thomas, D. C., Haile, R. W., & Duggan, D. (2005). Recent developments in genomewide association scans: a workshop summary and review. Am J Hum Genet, 77(3), 337-345 Abstract

Thompson, W. R. (1966). Multivariate experiment in Behavior Genetics. . In Cattell, R. B. (Ed.), Handbook of Multivariate Experimental Psychology (p711-731). Chicago, IL: Rand McNally.

Tikhonoff, V., Kuznetsova, T., Stolarz, K., Bianchi, G., Casiglia, E., Kawecka-Jaszcz, K., Nikitin, Y., Tizzone, L., Wang, J. G., & Staessen, J. A. (2003). beta-Adducin polymorphisms, blood pressure, and sodium excretion in three European populations. Am J Hypertens, 16(10), 840-846 Abstract

Tishkoff, S. A., Reed, F. A., Ranciaro, A., Voight, B. F., Babbitt, C. C., Silverman, J. S., Powell, K., Mortensen, H. M., Hirbo, J. B., Osman, M., Ibrahim, M., Omar, S. A., Lema, G., Nyambo, T. B., Ghori, J., Bumpstead, S., Pritchard, J. K., Wray, G. A., & Deloukas, (2007). Convergent adaptation of human lactase persistence in Africa and Europe. Nat Genet, 39(1), 31-40 Abstract

Trikalinos, T. A., Salanti, G., Khoury, M. J., & Ioannidis, J. (2006). Impact of violations and deviations in Hardy-Weinberg equilibrium on postulated gene-disease associations. Am J Epidemiol, 163(4), 300-309 Abstract

Tsai, S. J., Wang, Y. C., & Hong, C. J. (2001). Allelic variants of the alpha1a adrenoceptor and the promoter region of the alpha2a adrenoceptor and temperament factors. Am J Med Genet, 105(1), 96-98 Abstract

Tsai, S. J., Wang, Y. C., Chen, J. Y., & Hong, C. J. (2003). Allelic variants of the tryptophan hydroxylase (A218C) and serotonin 1B receptor (A-161T) and personality traits. Neuropsychobiology, 48(2), 68-71 Abstract

Tu, I. P., & Whittemore, A. S. (1999). Power of association and linkage tests when the disease alleles are unobserved. Am J Hum Genet, 64(2), 641-649 Abstract

Tukey, J. W. (1951). Components in regression. Biometrics, 7, 33-69

Turkheimer, E., & Gottesman, I. I. (1991). Is H2 = 0 a null hypothesis anymore? Behav. Brain Sci, 14, 410-411

Turkheimer, E., Haley, A., Waldron, M., D’Onofrio, B., & Gottesman, II. (2003). Socioeconomic status modifies heritability of IQ in young children. Psychol Sci, 14(6), 623-628 Abstract

Tzeng, J. Y., Wang, C. H., Kao, J. T., & Hsiao, C. K. (2006). Regression-Based Association Analysis with Clustered Haplotypes through Use of Genotypes. Am J Hum Genet, 78(2), 231-242 Abstract